Apparently, in the 1920s, when the uke was hugely popular, so many people played it so much and in so many place, that there were other people who simply couldn’t stand it.
This is documented in at least one book, one movie, and one song (that I know of).
In the Buster Keaton comedy, “Steamboat Bill, Jr.”, Buster returns from college with a loud striped jacket, a ridiculous thin moustache, and–yes, you guessed it, a ukulele.
Buster’s father, appalled, says to a friend, “If you say what you’re thinking, I’ll break your neck.”
And shortly after, snatches Buster’s uke and snaps it in two.
The ensuing ruckus causes his valet, Jeeves, to quit, and forces Bertie to moves to the countryside, to escape the threats of eviction from his landlord.
(Here's an Amazon link, if you want to read-n-laff.)
There’s a guy I’d like to kill
And if he doesn’t stop I will
He’s got a ukulele
And a voice that’s loud and shrill
The narrator of the song is certain that the jury and judge will understand the murder of the ukulele player and his never-ending refrain of “Vo-do-do.”
Here’s good old Frank Crummit playing it (on a ukulele–danger!) in 1927:
I’ll give you one way to avoid being the ukulele player that people want to kill (and you can still keep your bright striped jacket).
(That follow-up post is here).